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Trap columns for HPLC, UHPLC and LC/MS sample trapping

Trap Columns

Trapping is a chromatography technique that allows for the concentration or purification of a sample. A trap cartridge is a packed column bed loaded with a material to create desirable conditions for separating the target compound from the rest of the sample matrix. This is accomplished by selecting a packing material that has a strong affinity for the target compound, causing the analyte to be retained in the trap while the rest of the sample matrix flows through, or by selecting a material which has no affinity for the target compound but that binds other unwanted matrix components such as salts, detergents and contaminants.

Which Trap Column Do I Need?

Start with your flow, pressure and connection requirements to narrow down the trap hardware.

Very low-volume HPLC trapping
Minimal volume and direct connection to a standard 10-32 port

Quick-connect HPLC trapping
Replaceable cartridges with multiple bed-volume options

Nano-flow or volume-critical UHPLC
Ultra-low-volume trapping at UHPLC pressures

Larger packed beds at UHPLC pressure
Higher-capacity trapping for UHPLC applications

Manual, syringe-loaded or lower-pressure trapping
Manual or on-line sample concentration and purification

Looking for detergent or SDS removal?

Low/medium-pressure applications: OPTI-TRAP™ Cartridges   |   UHPLC/high-pressure applications: EXP® Trap Columns

Not sure which packing material to choose? Packing material depends on what you are trying to retain, concentrate, purify or remove.

Read the LC Trapping Guide   |   Contact Optimize Technologies

Browse All Trap Products Below

Universal LC Trap Columns

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