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Optimize your LC/MS Sample Preparation

Trapping - What is it? What are traps and how are they used?

The term "trap column" or "trap cartridge" refers to a packed bed with a suitable capacity to completely retain a given amount of target analyte within a sample. Trapping is often used in conjunction with mass spectrometry - the trap serves to clean up (and/or pre-concentrate) the analyte, while the MS handles detection and identification. The MS can also make up for low separation resolution and column efficiency which would not be acceptable with other modes of detection. In return for the trade-off in resolution, trap cartridges offer greatly reduced analysis time (a benefit common to all short/fast bed formats).

Topics covered:

  • Sample cleanup ("trap and dump”), desalting
  • LC separations on the MS timescale
  • Separation of a mixture of proteins
  • Trap cartridges as sample pre-concentrators (off-line and on-line)

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Happy Merry Everything + Holiday Closure

As the holiday season is upon us, we find ourselves reflecting on the past year and those who have helped to shape our business. It has been a[nother] strange year to say the least.We are grateful for your support and look forward to working with you in the years to come.Optimize will be closed from [...]

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Can you join us at ASMS next week?

We are excited to see friends, colleagues, partners, and [finally] meet face-to-face at booth #200.To schedule a meeting with us (virtually or on-site), click the link below. If you are unable to attend, keep an eye out for a post-ASMS email with details about the re-design of the EXP®2 Fitting Family and a link to [...]

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OPTI-MAX® Check Valve Cartridges for Dionex / Thermo Ultimate 3000 Pumps

Oregon City, OR – July 12, 2021 – Optimize Technologies, a leading provider of premium UHPLC, HPLC and LC/MS parts and consumables, is proud to introduce the new OPTI-MAX® EXP® 7mm Replacement Cartridges for Thermo/ Dionex/ Gyncotek Ultimate 3000 Series Pumps (OEM# 6041.2301).A brief overview: Priced significantly less than OEM and aftermarket options currently available. Each ball and seat is individually matched [...]

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New Catalog :: Available Now!

We are excited to finally, and formally, introduce our new catalog. You may already have a copy on your desk, downloaded the digital version, or seen our LCGC announcement a short time ago.If you have not received a printed copy or would like a copy sent to an address other than the one we have [...]

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Optimize Featured in Modern Machine Shop Magazine

Great article by Modern Machine Shop featuring our new facility. We couldn't agree more, automation is easier with FactoryWiz Monitoring. CNC Data Feeds Make Social Distancing Easier  ::  "Everyone has adapted differently to the pandemic, and we’re all using new tools to work. Automated machine shops have likely had an easier time of things, but automation is easier [...]

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COVID-19 Response

To the Optimize Community,We remain dedicated to you and are closely monitoring COVID-19 mandates and guidelines. We have implemented proactive measures identified by the CDC and our local health agencies to protect employees from contracting or spreading COVID-19.Currently, we do not anticipate any service delays or disruptions. We are committed to maintaining our business operations [...]

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Meet the EXP®2 Ti-LOK™ Fitting with Integral Ferrule

Oregon City, OR – July 23, 2018 – Optimize Technologies, a leading provider of premium UHPLC, HPLC and LC/MS parts and consumables, is proud to introduce the latest innovation in hand-tight UHPLC technology: the EXP2 Ti-LOK Fitting with Integral Ferrule.Evolving from Optimize Technologies’ original Titanium Hybrid Ferrule technology, the EXP2 Ti-LOK Fittings feature built-in PEEK ferrules and threaded nuts precision machined from titanium. [...]

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Welcome To Optimize Tech Online: General Information

How can I order Optimize products?Optimize products can be ordered through any Authorized Dealer in the United States and worldwide, by Phone: 800-669-9015, 503-557-9994 or Fax: 503-557-9995, and Online. If you do not have an Optimize dealer in your region, please contact us to order or for a dealer recommendation.How late can I place an [...]

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