Sample Concentration & Desalting
Sample concentration and desalting can be used to concentrate a dilute target, remove salts or non-volatile buffer components, or accomplish both in one trapping workflow. The basic approach is to retain the target, wash away unwanted matrix components, and then elute the target for downstream analysis.
Use the Peptide Concentration & Desalting Trap option available in OPTI-TRAP for this application.
Use the Protein Concentration & Desalting Trap option available in OPTI-TRAP for this application.
Peptide Concentration & Desalting Trap and Protein Concentration & Desalting Trap are application-specific chemistry identities. Similarly named generic chemistries are not automatically equivalent. For detailed chemistry guidance, use the Trap Chemistry Reference.
If pressure, flow, connections, method requirements, or another system constraint makes OPTI-TRAP unsuitable for your setup, contact Optimize Technologies before selecting another Trap family.
Use the Trap Compatibility & Holder Reference to confirm the correct cartridge and holder combination. For detergent-removal applications, use Detergent Removal. For the tandem SCX / peptide concentration-desalting workflow, use Peptide Fractionation & 2D LC Trapping.
Need help choosing the right approach? For small-molecule concentration/desalting, unclear chemistry, system or method constraints, exact configuration questions, or an uncertain cartridge/holder pairing, contact Optimize Technologies.