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RapidFire SPE Cartridges & Custom Packed Options

Agilent RapidFire systems use reusable solid-phase extraction (SPE) cartridges for high-throughput sample cleanup and mass spectrometry workflows.

Optimize Technologies manufactures RapidFire cartridges for Agilent. Standard Agilent RapidFire cartridge configurations should be purchased through Agilent. If your method requires a non-standard stationary phase, particle size, pore size, bed volume, or application-specific packing material, Optimize Technologies can work with you on a custom RapidFire cartridge.

Request a Custom RapidFire Cartridge

Standard Agilent RapidFire Cartridge Reference

Use the reference below to identify common standard Agilent RapidFire cartridge configurations. Standard catalog cartridges should be purchased through Agilent. If the standard configuration does not meet your method requirements, contact Optimize for a custom option.

Agilent Part Number Type Packing Bed Volume Typical Application / Notes
G9203A A C4, 20 µm 4 µL Oligonucleotides, peptide characterization, small molecules
G9525A A2 C4, 40 µm 4 µL Oligonucleotides, peptide characterization, small molecules
G9204A B Cyano 4 µL Alternative selectivity
G9205A C C18 4 µL Small molecules
G9526A C C18 12 µL Larger-bed C18 configuration
G9206A D Graphitized carbon 4 µL Hydrophilic compounds, small molecules
G9207A E C8 4 µL Peptide and protein characterization, small molecules
G9208A F Phenyl 4 µL Aromatic compounds
G9527A H6 HILIC 4 µL Hydrophilic compounds
G9211A O Blank 4 µL Troubleshooting / no stationary phase

Note: Agilent product specifications and availability can change. Use the linked Agilent part-number pages to confirm current standard-product information before ordering.

Looking for G9209A?

Agilent lists G9209A, the former Type H1 HILIC RapidFire cartridge, as obsolete and identifies G9527A, Type H6 HILIC, as its replacement. For the standard replacement configuration, purchase G9527A through Agilent.

Already Using a G9210A Custom RapidFire Cartridge?

G9210A is an Agilent custom RapidFire cartridge designation rather than one fixed stationary-phase configuration. Existing G9210A cartridges may use different packing materials, particle sizes, pore sizes, and bed volumes.

If Agilent has directed you to Optimize for an existing G9210A custom cartridge, send us the complete cartridge specification from your label, documentation, or previous order. Helpful information includes:

  • Stationary phase or packing material
  • Particle size
  • Pore size
  • Bed volume
  • Existing Agilent description or part number
  • Application or method information

Request a G9210A / Custom RapidFire Cartridge

Custom RapidFire Cartridges from Optimize Technologies

When a standard Agilent catalog cartridge does not match your method, Optimize can evaluate a custom RapidFire configuration around your application requirements.

Packing Chemistry

Evaluate alternative stationary phases, bonded phases, polymeric materials, or other application-specific sorbents.

Particle & Pore Size

Match particle and pore-size requirements to the analyte, retention mechanism, and method.

Bed Volume

Optimize custom RapidFire cartridges are available in 4 µL, 12 µL, and 20 µL bed volumes.

Application-Specific Packing

Custom configurations can be evaluated for specialized sample cleanup, enrichment, desalting, and other RapidFire workflows.

Availability of a specific packing material in a particular bed volume depends on the cartridge configuration and application requirements.

Need a Larger C4 RapidFire Cartridge?

Agilent G9203A is a standard Type A C4 cartridge with 20 µm packing and a 4 µL bed volume.

If your application requires additional bed volume, Optimize can evaluate custom C4 RapidFire cartridges in 12 µL or 20 µL configurations, along with other packing requirements appropriate for the application.

RapidFire Cartridges vs. OPTI-LYNX Micro Cartridges

Are OPTI-LYNX Micro cartridges interchangeable with RapidFire cartridges?

No. OPTI-LYNX Micro cartridges are designed for standard online trapping applications and are not directly interchangeable with the RapidFire cartridge changer. If you need a cartridge for a RapidFire instrument, request a RapidFire-specific configuration.

Frequently Asked Questions

Does Optimize manufacture RapidFire cartridges for Agilent?

Yes. Optimize Technologies manufactures RapidFire cartridges for Agilent.

Where should I purchase a standard Agilent RapidFire cartridge?

Purchase standard Agilent catalog configurations through Agilent using the corresponding part number.

What if Agilent does not offer the RapidFire configuration I need?

Contact Optimize Technologies. We can evaluate custom RapidFire requirements including packing chemistry, particle size, pore size, application-specific sorbents, and bed volume.

What custom RapidFire bed volumes does Optimize offer?

Optimize custom RapidFire cartridges are available in 4 µL, 12 µL, and 20 µL bed volumes. Packing and application requirements should be reviewed for the specific configuration.

I have a G9210A custom cartridge. What information should I send?

Send the complete packing description from your existing cartridge or documentation, including stationary phase, particle size, pore size, bed volume if known, and relevant application or method information.

Can I use an OPTI-LYNX Micro cartridge in a RapidFire instrument?

No. OPTI-LYNX Micro cartridges are not directly interchangeable with RapidFire cartridges.

Request a Custom RapidFire Cartridge

Do not see the RapidFire configuration your method requires? Send Optimize Technologies the information you have. You do not need every specification finalized before contacting us. Our team can review your existing cartridge, application, or method requirements and determine the appropriate next step.

Request a Custom RapidFire Cartridge