M45/45G, M501, 510, 590, 600/600E, 610, 6K/6KA, 515, 1515, 1525
Optimize Piston Seals are the longest lasting seals on the market. Machined from either of two proprietary polymer blends, UHMW-PE or ITB, Optimize Seals provide the ultimate in high pressure sealing capacity. For mostly aqueous buffered mobile phases, PTFE-based Improved PTFE Blend (ITB) seals are a superior choice for applications with elevated temperatures, high organic content, or when the broadest possible solvent compatibility is required. ITB™ seals tend to be softer than those made from UHMW-PE, making them more forgiving at high pressures where piston side-loading or misalignment may occur. This softer nature also leads to more shedding, but the ITB™ proprietary blend is designed to shed particles that are large enough to be caught at the surface of a standard 2 µm frit, not embed within it. For specific recommendation on a seal material for use with your particular mobile phase, consult our Solvent/Seal Compatibility Table.