“ We have been using custom packed OPTI-LYNX™ Quick-
Connect
columns and OPTI-SOLV® In-Line filters for several years
in our high-throughput LC/MS/MS analysis of ADME screening
samples. Problems with consistency and column longevity have
been virtually eliminated since we started using OPTI-LYNX
products. The Quick-Connect design makes changing columns fast
and easy, eliminating the need for any tools. We analyze tens
of thousands of samples each week (40-50,000). OPTI-LYNX columns
are a cost-effective option for our application due to the
large number of samples we analyze.”
Pfizer ADME
Technology Group
Biotrove
“ A custom miniaturized version of the OPTI-LYNX™ hardware,
specially designed to minimize dead volume, is the core of
the RapidFire™ high- throughput mass spectrometry system.
Together with our custom packing material, the OPTI-LYNX system
allows us to achieve extremely sharp chromatographic peaks
with minimal tailing at relatively low flow rates that are
compatible with atmospheric pressure mass spectrometry, eliminating
the need for post column splitting or diverting. Over the past
several years we have used the OPTI-LYNX system to analyze
over 3 million samples using the RapidFire system.”
Can ‘Jon’ özbal, Ph.D.
Senior Director and RapidFire Business Manager
Biotrove, Inc.
Berlex
“ The Berlex ACS group has worked with Optimize Technologies
on a number of custom fabrication projects of varying scope.
The projects have ranged from the design, engineering and fabrication
of complex reaction block and shaker systems, to the development,
testing and finally the bulk production of individual reaction
tubes (supplied at more than 300K per year). Optimize personnel
have always provided creative cost effective design options
and high quality products. The experience of working with Optimize
Technologies on custom projects has been very rewarding.”
Karen May, Scientific Unit Head
Automated Chemical Synthesis Group
Berlex Biosciences
Alkermes
“Optimize Technologies developed a custom polysulfone
‘dose
piston’ with a stainless steel flow restrictor installed
at the outlet. This custom piece is used to dose our pharmaceutical
dry powdered product into a vial via a sterile filling process.
The Optimize disposable dose piston eliminates pre-assembly
and testing associated with our old assemblies, which can take
several hours. The new dose piston assembly also is void of
integrity issues as the stainless steel filter is far more
robust than the pleated filter we were assembling. We save
time and money due to relative ease of installation and it
eliminates the issues we were incurring with filter damage
prior or during a GMP production run.”
Jay Carstens
Process Engineering, Alkermes, Inc.
Cardinal Health
“ The Optimize OPTI-LYNX™ filter lasts twice as
long as previous filter, typically two weeks instead of just
one. The ease of use is the best part. It's just a matter of
twisting it on and off, and when you're dealing with radioactivity,
speed is essential to decrease your exposure."
Andy Rodriquez
Site Supervisor, Target F18 Production
Cardinal Health
Testimonials
